We've put in more than 3 years of work to develop an algorithm to maximize the number of eggs that fertilize when performing Conventional IVF insemination (meaning without using assisted fertilization technique called ICSI).
Conventional IVF is the traditional method of fertilizing eggs, performed by adding between 50,000 to 100,000 sperm cells to each egg and allowing natural fertilization to occur. Some patients and clinics prefer this method of fertilizing eggs because it resembles the natural fertilization events inside the woman's body and some studies show that the resulting embryos are of higher quality. The drawback to Conventional IVF is that fertilization is unpredictable, some patients will have good fertilization rates, some fair, some poor, and some with complete failure of fertilization (zero % fertilized).
From our time-consuming studies, we were able to determine the type of sperm that has the potential to fertilize the egg and were able to calculate the number of sperm cells to add to each egg based on the quality of sperm thereby maximizing fertilization potential.
Algorithm IVF is the system we developed wherein the number of sperm used in inseminating the eggs is adjusted based on the quality of motile sperm instead of the traditional 50,000 to 100,000 sperm cells per egg. Using Algorithm IVF, we were able to achieve consistently high fertilization rates for all types of sperm samples, even those with less than 4% strict morphology which had been problematic with Conventional IVF because they often result in poor fertilization or even complete failure of fertilization.